MATLAB: Problem with symbolic tool

MATLABMATLAB and Simulink Student Suitesymbolicsymengine

Hi, i have a problem with the matlab's symbolic tool, using R2018a version (the previously version was not effected by this issue). When I try to create a symbol matlab run for long time and then display this message:
>> syms x
Error using mupadmex
Internal error with symbolic engine. Quit and restart MATLAB.
Error in sym>tomupad (line 1219)
    S = mupadmex(numeric2cellstr(x));
Error in sym (line 211)
                S.s = tomupad(x);
Error in syms (line 201)
toDefine = sym(zeros(1, 0));
Has Anyone the same problem and/or can help me?
Thanks.
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