MATLAB: What is the best method to solve large linear system equation (Ax=b) (A:million~ by million~)

gpuMATLABsystem matrix

The maxtix A is sparse from finite element analysis.
I have used backslash to solve the equation but I want to reduce the calculation time.
I also tried to use GPU acceleration but there is a memory limitation with Titan xp with 12Gb memory.

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