When I write GUIs I usually specify the minimum property descriptions necessary for each style, then at the end of my initialization code I call a custom function to set my standard defaults.
This function takes no arguments (except optionally a figure handle for limiting the search), but uses FINDALL to parse through each style of uicontrol and assign the defaults like fontsize, backgroundcolor, etc.
It sounds like you could benefit from writing such a function too!
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