I am currently determining kinetics for a simple reversible first order system.
I am trying to fit my rate constants (k) so the model matches my experimental data.
However, I am currently getting the next message:
Local minimum possible.
lsqcurvefit stopped because the size of the current step is less than
the default value of the step size tolerance.
<stopping criteria details>
I think my fit is not optimal and I am (probably?) currently at a local minimum.
Hence my question: how can I fit these parameters to an absolute minimum?
Besides the message, my fit is terrible: (stars = experimental data, red line = model)
I added my scripts in case someone wants to take a look.
Thanks in advance!
Best Answer