MATLAB: Is there a function to identify and find the area under peaks in chromatography data

Bioinformatics Toolbox

I have some chromatography data, and need to identify peaks in this data, and determine the area under each.

Best Answer

The ability to identify and integrate the area under peaks in chromatography data is not available in MATLAB.

One can use the MSVIEWER function within the Bioinformatics Toolbox to view the data and manually add markers at the start and end of each peak. These marker's locations can then be exported to the workspace, and the TRAPZ function used to numerically integrate the area under each peak indicated.

Before doing these things, the MSBACKADJ function can be used to help remove any bias in the signal, if required.

Related Solutions

MATLAB: How to integrate the area under a curve (from experimental data) with X & Y boundary conditions

Use trapz....

check the link:

https://in.mathworks.com/matlabcentral/answers/154089-area-under-curve-no-function

MATLAB: Getting the area under the peaks

I would first identify the low points (‘valleys’) by inverting your signal and then using the Signal Processing Toolbox findpeaks function to locate them. Then integrate between those points to identify the peaks.

Example —

t = linspace(0, 10*pi, 250);                        % Create Data

s = sin(t) + 0.2*cos(5*t) + 2;                      % Create Data
figure(1)
plot(t, -s)
grid
[Vlys, Idx] = findpeaks(-s, 'MinPeakHeight',-1.1);
Area = cumtrapz(t,s);
idxvct = [1 Idx length(s)];
for k1 = 1:length(idxvct)-1
    PkAreas(k1) = Area(idxvct(k1+1)) - Area(idxvct(k1));
end

The ‘PkAreas’ vector will have the areas of the peaks.

You will have to adapt this to your data. Be sure to plot the negative of your data first so you can see and set the appropriate arguments for findpeaks.

Best Answer

Related Solutions

MATLAB: How to integrate the area under a curve (from experimental data) with X & Y boundary conditions

MATLAB: Getting the area under the peaks

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