If you have R2018b or later, you can fread as uint16 and then typecast into half type. E.g.,
>> d = [-inf -pi 0 pi inf nan]
d =
-Inf -3.1416 0 3.1416 Inf NaN
>> h = half(d)
h =
1×6 half row vector
-Inf -3.1406 0 3.1406 Inf NaN
>> u = storedInteger(h)
u =
1×6 uint16 row vector
64512 49736 0 16968 31744 65024
>> H = half.typecast(u)
H =
1×6 half row vector
-Inf -3.1406 0 3.1406 Inf NaN
If you don't have R2018b or later, then the half type is not availalbe and you will be stuck with converting the values to single or double precision if you want to work with them in MATLAB. In that case, use fread as uint16 and then use the following FEX submission to turn the values into single or double:
E.g.,
>> S = halfprecision(u,'single')
S =
1×6 single row vector
-Inf -3.1406 0 3.1406 Inf NaN
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