MATLAB: How to multiply part of a matrix with another matrix

MATLABmatrix multiplication

I have these two matrices M1 and M2. I'm trying to multiply M1 with the first two columns of M2 element by element (while not using a for loop). I've tried the dot multiplier and that hasn't worked. The result should just be one matrix. 
M1 = [4 5; 3 1; 2 7]; 
M2 = [1 5 7; 3 10 4; 8 7 2];

Best Answer

result = M1 .* M2(:,1:2);
If you want to replace part of M2 with this result, then simply
M2(:,1:2) = M1 .* M2(:,1:2);
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