MATLAB: Do I receive an error or an incorrect plot when using DIMERCOUNT in Bioinformatics Toolbox 1.1 (R14)

Bioinformatics Toolboxcodoncountdimercountdnadyadgeneticrnasequencessequencing

I am using the DIMERCOUNT function to count dimers in a sequence that includes gaps and/or ambiguous bases. I receive an error when working with a sequence including gaps (represented with a hyphen), and an incorrect plot while working with sequences including ambiguous bases. For example, when I type the following sequence:
dimercount('TAG-TGGCCAAGCGAGCTTG')
I expect a warning about gaps and/or ambiguous bases, as described in the documentation, and then a list of dimers, including an "Others" field. For the sequence given above, I would expect the following output:
 Warning: Ambiguous symbols '-' appear in the sequence. These will be in Others.
 In dimercount at 132
 ans = 
         AA: 1
         AC: 0
         AG: 3
         AT: 0
         CA: 1
         CC: 1
         CG: 1
         CT: 1
         GA: 1
         GC: 3
         GG: 1
         GT: 0
         TA: 1
         TC: 0
         TG: 2
         TT: 1
     Others: 2
Instead, the DIMERCOUNT function produces an error of the following form:
 ??? Attempted to access buckets(16,16); index out of bounds because size(buckets)=[15,15].
 Error in ==> dimercount at 100
     buckets(dna(count),dna(count+1)) = buckets(dna(count),dna(count+1)) + 1;
 Error in ==> basecount_dimercount_error at 35
 dch=dimercount(mySequence)
If I use a different symbol to represent the gaps, or work with a sequence including ambiguous bases, I do not receive this error. If I use the 'Chart' option with a sequence containing ambiguous bases, however, the "Others" field is missing from the resulting plot.

Best Answer

This bug has been fixed in Release 14 Service Pack 3 (R14SP3). For previous product releases, read below for any possible workarounds:
This problem has been fixed in Bioinformatics Toolbox 2.1 (R14SP2+). For previous versions, read the following:
There is a bug in Bioinformatics Toolbox 1.1 (R14) when using DIMERCOUNT with sequences containing gaps and/or ambiguous bases.
To work around the error produced when working with sequences with gaps, substitute a different character for the hyphen, such as the letter X (which normally does not represent a base) or a space.
There are no known workarounds for the issue with plots.
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