This can be done using the RF Toolbox 2.5 (R2009a). The following functions can be used to realize this application.
S2MM - Convert 4N-port single-ended S-parameters to 4 2N-port mixed-mode S-parameters.
SMM2s - Convert 4 2N-port mixed-mode S-parameters to single-ended S-parameters.
S2DD - Convert 4-port S-parameters to differential 2-port S-parameters Sdd.
S2DC - Convert 4-port S-parameters to cross mode 2-port S-parameters Sdc.
S2SCD - Convert 4-port S-parameters to cross mode 2-port S-parameters Scd.
S2SCC - Convert 4-port S-parameters to common mode 2-port S-parameters Scc.
S2TF - Calculate transfer function from 2-port S-parameters.
In order to model mixed-mode simulation, there might be multiple approaches to go about it.
The RF Toolbox documentation includes an example "Modeling a High-Speed Backplane (Part 2: 4-Port S-Parameters to a Rational Function Model)" showing a differential-model application.
If you replace S2SDD with S2SCC, you will get the common-mode. Please note that when using S2TF, the impedances are different for differential-mod and common-mode:
Zs(common-mode) = (Zs1 * Zs2)/(Zs1 + Zs2)
Zl(common-mode) = (Zl1 * Zl2)/(Zl1 + Zl2)
Z0(common-mode) = Z0/2
vs.
Zs(differential-mode) = Zs1 + Zs2
Zl(differential -mode) = Zl1 + Zl2
Z0(differential -mode) = 2*Z0
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