I'm going to write an answer using vectors.
Let $O$ be the intersection point of $AC, BD$.
Let $$\vec{OA}=\vec{a}, \vec{OB}=\vec{b}, \vec{OC}=k\vec{a}, \vec{OD}=l\vec{b}$$
where $k,l\lt 0.$
Letting $E,F,G,H$ be the midpoints of $AB, BC, CD, DA$ respectively, we have
$$\vec{OE}=\frac{1}{2}\vec a+\frac 12\vec b,\vec{OF}=\frac 12\vec b+\frac k2\vec a, \vec{OG}=\frac k2\vec a+\frac l2\vec b, \vec{OH}=\frac 12\vec a+\frac l2\vec b.$$
Letting $I$ be the intersection point of $EG, FH$, there exist $m,n$ such that
$$\vec{EI}=m\vec{EG}, \vec{FI}=n\vec{FH}.$$
The former gives us
$$\vec{OI}-\vec{OE}=m\left(\vec{OG}-\vec{OE}\right)\iff \vec{OI}=(1-m)\vec{OE}+m\vec{OG}=\frac{1-m+mk}{2}\vec a+\frac{1-m+ml}{2}\vec b.$$
The latter gives us
$$\vec{OI}-\vec{OF}=n\left(\vec{OH}-\vec{OF}\right)\iff \vec{OI}=(1-n)\vec{OF}+n\vec{OH}=\frac{k-kn+n}{2}\vec a+\frac{1-n+nl}{2}\vec b.$$
Now since $\vec a$ and $\vec b$ are linearly independent, the following has to be satisfied :
$$\frac{1-m+mk}{2}=\frac{k-kn+n}{2}\ \text{and} \frac{1-m+ml}{2}=\frac{1-n+nl}{2}.$$
These give us $m=n=1/2$ since $(k,l)\not=(-1,-1).$
Hence, we get
$$\vec{OI}=\frac{k+1}{4}\vec a+\frac{l+1}{4}\vec b.$$
On the other hand, letting $P,Q$ be the midpoints of $AC, BD$, we have
$$\vec{OP}=\frac{k+1}{2}\vec a, \vec{OQ}=\frac{l+1}{2}\vec b.$$
Finally, we obtain
$$\vec{PI}=\frac 12\vec{PQ}.$$
Since this represents that $I$ is on the line $PQ$, we now know that we get what we want. Q.E.D.
P.S. If $(k,l)=(-1,-1)$, then $ABCD$ is a parallelogram, which is an easy case.
Given two quadrilaterals $ABCD$ and $EFGH$, with side lengths equal, (i.e. $d(A,B)=d(E,F)$, etc.) then $ABCD \cong EFGH$ if and only if the diagonals have equal length: $d(A,C)=d(E,G)$ and $d(B,D)=d(F,H)$, where $d$ is the distance between the points.
The forward implication is obvious.
To see the converse, we first notice that the diagonal's length being equal gives us a few congruent triangles. Namely, $\triangle ABC \cong \triangle EFG$, $\triangle ACD \cong \triangle EGH$ from $d(A,C)=d(E,G)$, by the good old SSS property.
Using only the one diagonals being equal, we would have two possible quadrilaterals from these facts. They come from reflecting one of the triangles over the diagonal.
![Two quadrilaterals, clearly not congruent, outlined in blue and green.](https://i.stack.imgur.com/EEK5i.png)
Next, we see that we are given the distance between $D$ and $B$. Therefore, we are forced in which of these two options must be our congruent quadrilateral. The only way that both quadrilaterals could be acceptable is if $B$ is the proper distance from $D$ in both. But this will force $B$ onto the diagonal between $A$ and $C$, which contradicts the definition of a polygon (giving you a triangle instead), and finishes the proof.
I hope this was helpful. I believe a slight variation of this will work if you know the length of one diagonal, say $d(A,C)$ and the angle $\angle BCD$ or $\angle BAD$. It would seem reasonable that the same will hold if you know area, the four sides and a diagonal also. The fact that you have two possibilities right away from one triangle gives you most of the information. Also, it is pretty clear that the reflection over one of the diagonals will always produce one convex quadrilateral and one not.
Best Answer
Hint: If your four points are $a, b, c, d$, then the midpoints, in order around the quad, are $$ p = \frac{1}{2}(a+b), q = \frac{1}{2}(b+c), r = \frac{1}{2}(c+d), s = \frac{1}{2}(d+a). $$
For $pqrs$ to be a parallelogram, you need the edge from $p$ to $q$ to have the same direction vector as the edge from $s$ to $r$; you need a similar thing to hold for the edges from $q$ to $r$ and $p$ to $s$.
What's the direction vector of the edge from $p$ to $q$? Can you express it in terms of $a, b, c, d$?