Let the circle be the unit circle, and take the parabola to have the equation $y-k=a(x-h)^2$, with $a\neq 0$. Note that the slope of the line tangent to the parabola at $(x,y)$ is given by $m = 2 a (x-h)$.
Let $T(\cos\theta,\sin\theta)$ be the point of tangency. (We may assume throughout that $\sin\theta \neq 0$, since our (presumably non-degenerate) parabola has no vertical tangents. Note also that distinct points of intersection must correspond to distinct $x$ coordinates.) Then, as $T$ must satisfy the parabola equation, we have
$$\sin\theta - k = a ( \cos\theta - h )^2 \qquad (1)$$
Now, the line tangent to the circle at $T$ necessarily has slope $-\cot\theta$; equating this with the slope relative to the parabola gives
$$\cos\theta = -2 a \sin\theta (\cos\theta - h ) \qquad (2)$$
We can solve $(2)$ for $h$, and then $(1)$ for $k$:
$$
h = \frac{\cos\theta \left( 1 + 2 a \sin\theta \right)}{2a\sin\theta}
\qquad
k = \frac{ 4 a \sin^3\theta - \cos^2\theta }{4a\sin\theta^2}$$
whence the parabola equation becomes
$$y \sin\theta = a x^2 \sin\theta - x \cos\theta \left( 1 + 2 a \sin\theta \right) + 1 + a \cos^2\theta \sin\theta $$
Using that equation to eliminate $y$ in $x^2+y^2=1$ gives this polynomial equation in $x$:
$$\left( x - \cos\theta \right)^2 \left(
\left( a \left( x - \cos\theta \right)\sin\theta - \cos\theta\right)^2
+ \sin^2\theta \left( 1 + 2 a \sin\theta \right)\right) = 0 \qquad (3) $$
For the second factor of $(3)$ to have any roots requires the quantity $b := 1+2a\sin\theta$ to be non-positive. If $b$ vanishes, we get the double root $x=-\cos\theta$ (the mirror image of $x=\cos\theta$) corresponding to a second point of circle-parabola tangency. For us to have a point of non-tangent intersection, we require $b$ to be strictly negative, and $x=\cos\theta$ to be a root of that second factor. The latter condition implies, by substitution:
$$2a\sin^3\theta=-1$$
giving $b=-\cot^2\theta$, which is strictly negative (and defined) for $\theta \neq n \pi/2$. Moreover, equation $(3)$ reduces nicely to
$$0 = (x-\cos\theta)^3\left(x-4\cos^3\theta+3\cos\theta\right) = (x-\cos\theta)^3(x-\cos 3\theta)$$
providing the root $x=\cos3\theta$. Double-checking with the parabola equation, we see that the corresponding $y$ value should be $-\sin3\theta$; thus, we can write the second point of intersection as $S(\cos(-3\theta), \sin(-3\theta))$.
The final parabola equation itself is
$$ 2 y \sin^3\theta = - \left( x - \cos^3\theta \right)^2 + \sin^4\theta\left( 3 - \sin^2\theta \right)$$
Here's an animation:
(Animation, and interstitial symbol-crunching, courtesy of Mathematica.)
Best Answer
If $A(at^2,2at)$ is one of the extremities of the focal chord, we know that the other end will be $B\left(\dfrac{a}{t^2}, -\dfrac{2a}{t}\right)$
Let the circle with $AB$ as diameter intersect the parabola at $C(t')$. Since $\angle ACB$ is a right angle, we have $\dfrac{2}{t+t'} \times \dfrac{2}{t'-\dfrac{1}{t}}=-1$
or $t'^2+ \left(t-\dfrac{1}{t} \right)t'+3 =0$
We see that this will have two real roots when $\left(t-\dfrac{1}{t} \right)^2 > 12$