I have two groups of curves that are clearly different. How I can calculate p-value?
Green and blue curves is the average of about 10 curves from each group. The filled area is standard deviation. And the black curve at the bottom is the difference between average curves.
Best Answer
If the curves represented something like a distribution, you could use Komogorov- Smirnoff test wiki link, but it doesn't look like they are distributions.
Depending on what it is about the curves you're trying to capture, you may consider simply reducing it to a simpler description of the curve y(x); say max(y), or min(y), or avg(y) over the interval x. (You may even consider a mesure like the diff(y_green - y_blue) over samples in x.) Then you would effectively have 2 samples, and could proceed with standard techniques from there.