Solved – How to compare paired percentages (can I use the Wilcoxon signed-rank test?)

nonparametricpercentagerwilcoxon-signed-rank

Imagine I would like to test whether the blood oxygen saturation differs significantly between left and right arm. Now, imagine that:

  • All measurements are percentages
  • The differences between pairs show positive skewness and bimodality
  • The sample size is composed by 50 volunteers (50 left + 50 right =
    50 pairs of measurements)
  • I have not to assume that the difference is clinically significant (only statistically)

My question is: is the Wilcoxon signed-rank test a good choice to test that, or are percentages not tested well by it?

(I use R)

I read those Q&A, but my doubts are still there mainly because I do not understand if a nonparametric test would be more appropriate and my data would be strictly percentages: Percentages from non binomial data: is ANOVA / Kruskal-Wallis appropriate?, Using ANOVA on percentages? and Wilcoxon signed-rank test for proportion variable response?

Best Answer

Wilcoxon signed rank test and all such univariate analyses (ANOVA, t-Test, etc.) can be analyzed using regression. You will probably need to do a log transformation in the percentages if they are your outcome (DV) and/or use logistic regression if the arm is a dichotomous variable.

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