Hi, I'm following the instruction of bacterial PK-PD model based on the previous model
(Nielsen, E. I. et al. Semimechanistic pharmacokinetic/pharmacodynamic model for assessment of activity of antibacterial agents from time-kill curve experiments. Antimicrobial Agents and Chemotherapy. 51:128-136.) https://www.mathworks.com/help/simbio/ug/model-views.html
In this instruction, there are two compartments named to Central and Biophase compartment and are assumed that the presence of the Biophase compartment does not affect the mass balance.
When should I meet this condition "some compartment doesn't affect the mass balance" ?
I would be appreciate if you could share some examples.
Thanks
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